An HIV vaccine: where is it?
Since HIV surfaced in the 1980s, 60 million worldwide have been infected and 20 million have died. Currently about 3 million die each year from HIV and in some parts of Africa HIV is an epidemic. World-wide HIV is the fourth leading cause of death and the leading cause of death in sub-Saharan Africa. Once HIV infection carried with it an almost automatic death sentence, and in many parts of Africa this remains true today, although the antiretroviral drugs that help prolong the lives of the afflicted, that are commonly available here in the United States and Europe, are beginning to reach poorer African countries with reduced costs. Since these drugs to not cure the disease, but prolong the lives of those infected, the real hope for HIV remains in developing an effective and safe vaccine. As you know, in the United States the most common form of AIDS transmission has been through homosexual contact, but in Africa, the most common transmission mode has been heterosexual transmission. In Sub-Saharan Africa there are an estimated 500 000 infants who contract HIV each year. Transmission to children can occur in utero, at birth or through breast feeding. The antiretroviral drugs prevent transmission from mother to infant, so pregnant women in Africa get a high priority for antiretroviral drug therapy, even thought the drugs are not yet in sufficient supply to reach all those infected.
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